Voltage-gated Na_ channels are open during the depolarizing phase, and voltage-gated K_ channels are open during the repolarizing phase of an action potential.

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1 Voltage-gated Na_ channels are open during the depolarizing phase, and voltage-gated K_ channels are open during the repolarizing phase of an action potential.

2 In some electrical synapses (gap junctions), ions may flow equally well in either direction, so either neuron may be the presynaptic one. At a chemical synapse, one neuron releases neurotransmitter and the other neuron has receptors that bind this chemical. Thus, the signal can proceed in only one direction.

 

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